Ralph H. Loring, PhD
Associate Professor
Department of Pharmaceutical Sciences, Faculty, School of Pharmacy and Pharmaceutical Sciences
Office: 140 TF Room 166
Email: [email protected]
Phone: 617-373-3216
Associate Professor
Department of Pharmaceutical Sciences, Faculty, School of Pharmacy and Pharmaceutical Sciences
Office: 140 TF Room 166
Email: [email protected]
Phone: 617-373-3216
Selected Publications:
Moaddel R, Sharma A, Huseni T, Jones GS, Jr., Hanson RN, Loring RH. Novel biotinylated phenyl-arsonous acids as bifunctional reagents for spatially close thiols: studies on reduced antibodies and the agonist binding site of reduced Torpedo nicotinic receptors. Bioconjug Chem 10:629-37 (1999).
Sweileh W., Wenberg K., Xu J., Forsayeth J., Hardy S., and Loring, R.H. Multistep Expression and Assembly of Neuronal Nicotinic Receptors is Both Host-Cell and Receptor-Subtype Dependent. Mol. Brain Res., 75:293-302 (2000).
S. Goklany, R.H. Loring, J. Glick, C. W.T. Lee-Parsons. Assessing the limitations to terpenoid indole alkaloid biosynthesis in Catheranthus roseus hairy root cultures through gene expression profiling and precursor feeding. Biotechnology Progress, 25:1289-96 (2009).
V. Hosur, S. Leppanen, A. Abutaha, and R.H. Loring. Gene regulation of α4β2 nicotinic receptors: Microarray analysis of nicotine-induced α4β2 up-regulation and anti-inflammatory effects. Journal of Neurochemistry, 111: 848-58, (2009).
V. Hosur and R.H. Loring. α4β2 Nicotinic Receptors Partially Mediate Anti-Inflammatory Effects through Janus Kinase 2 (JAK2) – Signal Transducer and Activator of Transcription 3 (STAT3) but Not Calcium or cAMP Signaling. Molecular Pharmacology 79:167-74. (2011).