Can psilocybin — the main element in magic mushrooms — be the key to treating head injuries?

Key Takeaways

  • This is the first report to find that PSI can treat brain injury, given its anti-inflammatory properties and promotion of neuroplasticity and cell growth.

By Erin Kayata

Mild repetitive head injuries do more than just cause short-term issues with cognition, behavior and motor skills. They also lead to an increased risk of dementia, Parkinson’s disease and chronic traumatic encephalopathy, and cost billions of dollars in health care.

There is no medical treatment for these types of injuries but new preliminary research out of Northeastern University shows a solution may lie in a surprising place: psilocybin, the psychedelic found in drugs like magic mushrooms.

A group of researchers including Northeastern psychology professor Craig Ferris tested the healing effects of psilocybin on adult female rats. After these rats suffered mild head injuries, researchers found that being treated with psilocybin helped restore normal brain function.

“I was absolutely stunned,” Ferris said. “It actually improves these neuroradiological measures associated with head injury.”

The research has not yet been peer reviewed, but appeared in PubMed as a preprint. It could show promise as a potential course of treatment for mild repetitive head injuries, Ferris said.

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